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Background
[Isoform 1]: Adds and repairs the conserved 3′-CCA sequence necessary for the attachment of amino acids to the 3′ terminus of tRNA molecules, using CTP and ATP as substrates. [Isoform 2]: Adds 2 C residues (CC-) to the 3′ terminus of tRNA molecules instead of a complete CCA end as isoform 1 does (in vitro).