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Background
Required for leukotriene biosynthesis by ALOX5 (5-lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes.
Product overview
Product Name
Arachidonate 5-Lipoxygenase-Activating Protein
Code
E4982Hu
Assay type
Sandwich
Size
96 test
Sensitivity
1.41ng/L
Reactivity
Human
Detection range
1.41ng/L
Sample type
Serum, plasma, cell culture supernates
Synonyms
ALOX5AP;Arachidonate 5-lipoxygenase-activating protein;FLAP;MK-886-binding protein