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Background
Thought to form a receptor-activated non-selective calcium permeant cation Channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Has also been shown to be calcium-selective (By similarity). May also be activated by intracellular calcium store depletion. Mediates calcium-dependent phosphatidylserine externalization and apoptosis in neurons via its association with PLSCR1 (By similarity).
Product overview
Product Name
Short Transient Receptor Potential Channel 5
Code
E4836Hu
Assay type
Sandwich
Size
96 test
Sensitivity
0.032ng/ml
Reactivity
Human
Detection range
0.032ng/ml
Sample type
Serum, plasma, cell culture supernates
Synonyms
hTRP5;hTRP-5;Short transient receptor potential Channel 5;Transient receptor protein 5;TRP-5;TRPC 5;TRPC5