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Background
Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival. Enhances the production of IL4 and IL10 in T-cells in conjunction with TCR/CD3 ligation and CD40L costimulation (PubMed: 8617933). Isoform 3 enhances CD40L-mediated activation of NF-kappa-B and kinases MAPK8 and PAK2 in T-cells (PubMed: 15067037).
Product overview
Product Name
T-Cell-Specific Surface Glycoprotein Cd28
Code
E4196hu
Assay type
Sandwich
Size
96 test
Sensitivity
0.024ng/ml
Reactivity
Human
Detection range
0.024ng/ml
Sample type
Serum, plasma, cell culture supernates
Synonyms
CD 28;CD antigen CD28;CD28;T-cell-specific surface glycoprotein CD28;TP44
