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Background
Receptor for netrin required for axon guidance. Mediates axon attraction of neuronal growth cones in the developing nervous system upon ligand binding. Its association with UNC5 proteins may trigger signaling for axon repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. Implicated as a tumor suppressor gene.
Product overview
Product Name
Netrin Receptor Dcc
Code
E4180hu
Assay type
Sandwich
Size
96 test
Sensitivity
11.13ng/L
Reactivity
Human
Detection range
11.13ng/L
Sample type
Serum, plasma, cell culture supernates
Synonyms
Colorectal cancer suppressor;DCC;Immunoglobulin superfamily DCC subclass member 1;Netrin receptor DCC;Tumor suppressor protein DCC
