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Background
Involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T-lymphocyte (CTL) and NK cell (PubMed: 8673704). Cell surface receptor for NECTIN2. Upon ligand binding, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Competes with PVRIG for NECTIN2-binding (PubMed: 26755705).
Product overview
Product Name
Cd226 Antigen
Code
E4093hu
Assay type
Sandwich
Size
96 test
Sensitivity
0.27ng/ml
Reactivity
Human
Detection range
0.27ng/ml
Sample type
Serum, plasma, cell culture supernates
Synonyms
CD 226;CD antigen CD226;CD226;CD226 antigen;DNAM-1;DNAX accessory molecule 1