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Background
Associates with IFNGR1 to form a receptor for the cytokine interferon gamma (IFNG) (PubMed: 8124716, PubMed: 7673114,PubMed: 7615558). Ligand binding stimulates activation of the JAK/STAT signaling pathway (PubMed: 8124716, PubMed: 7673114, PubMed: 15356148). Required for signal transduction in contrast to other receptor subunit responsible for ligand binding (PubMed: 7673114).
