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Background
Critical component of the visual transduction cascade, controlling the calcium concentration of outer segments during light and darkness. Light causes a rapid lowering of cytosolic free calcium in the outer segment of both retinal rod and cone photoreceptors and the light-induced lowering of calcium is caused by extrusion via this protein which plays a key role in the process of light adaptation. Transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+).
Product overview
Product Name
Sodium/Potassium/Calcium Exchanger 1
Code
E2539Hu
Assay type
Sandwich
Size
96 test
Sensitivity
0.021ng/ml
Reactivity
Human
Detection range
0.021ng/ml
Sample type
Serum, plasma, cell culture supernates
Synonyms
CSNB1D;HsT17412;KIAA0702;Na(+)/K(+)/Ca(2+) exchange protein 1 antibody;NCKX;NCKX1;Retinal rod Na Ca+K exchanger antibody;Retinal rod Na+/Ca+/K+ exchanger antibody;RODX;SLC24A1;Sodium/potassium/calcium exchanger 1 antibody
