Catalyzes the formation of the signaling molecule cAMP (PubMed: 12609998, PubMed: 15659711, PubMed: 24616449, PubMed: 25040695, PubMed: 24567411). May function as sensor that mediates responses to changes in cellular bicarbonate and CO(2) levels (PubMed: 15659711, PubMed: 17591988). Has a critical role in mammalian spermatogenesis by producing the cAMP which regulates cAMP-responsive nuclear factors indispensable for sperm maturation in the epididymis. Induces capacitation, the maturational process that sperm undergo prior to fertilization (By similarity). Involved in ciliary beat regulation (PubMed: 17591988).
Related Resources
