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Background
Component of a transcriptional repressor complex together with MAX (PubMed: 8425218). In complex with MAX binds to the core DNA sequence 5′-CAC[GA]TG-3′ (PubMed: 8425218). Antagonizes MYC transcriptional activity by competing with MYC for MAX binding (PubMed: 8425218). Binds to the TERT promoter and represses telomerase expression, possibly by interfering with MYC binding (PubMed: 12837246).
Product overview
Product Name
Max Dimerization Protein 1
Code
E1615Hu
Assay type
Sandwich
Size
96 test
Sensitivity
3.34ng/L
Reactivity
Human
Detection range
3.34ng/L
Sample type
Serum, plasma, cell culture supernates
Synonyms
Max dimerization protein 1;Max dimerizer 1;MXD 1;MXD1;Protein MAD