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Background
Cleaves aggrecan, a cartilage proteoglycan, at the ‘1938-Glu-|-Leu-1939’ site (within the chondroitin sulfate attachment domain), and may be involved in its turnover (By similarity). Has angiogenic inhibitor activity. Active metalloprotease, which may be associated with various inflammatory processes as well as development of cancer cachexia. May play a critical role in follicular rupture.
Product overview
Product Name
A Disintegrin and Metalloproteinase with Thrombospondin Motifs 1
Code
E1155Hu
Assay type
Sandwich
Size
96 test
Sensitivity
0.025ng/ml
Reactivity
Human
Detection range
0.025ng/ml
Sample type
Serum, plasma, cell culture supernates
Synonyms
A disintegrin and metalloproteinase with thrombospondin motifs 1;ADAMTS 1;ADAM-TS 1;ADAMTS1;ADAMTS-1;ADAM-TS1;METH-1