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Background
Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly. Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Ligand for integrin alpha-L/beta-2 involved in memory T-cell and neutrophil transmigration. Involved in platelet activation.
Product overview
Product Name
Junctional Adhesion Molecule A
Code
E0323Bo
Assay type
Sandwich
Size
96 test
Sensitivity
5.16ng/L
Reactivity
Bovine
Detection range
5.16ng/L
Sample type
Serum, plasma, cell culture supernates
Synonyms
CD antigen CD321;F 11R;F11R;JAM-1;JAM-A;Junctional adhesion molecule 1;Junctional adhesion molecule A
