Read over 350 inspirational, peer-reviewed publications and discover the power of RPA.
Review papers
Current trends and challenges in bioelectrochemistry for non-invasive and early diagnosis
Author: Campuzano S, Yanez-Sedeno P, Pingarron JM.
Electrochemical (bio)sensing for early and minimally invasive clinical diagnosis. Latest advances, current trends, potentiality and existing challenges. Judicious design of …
Direct surface-enhanced Raman scattering (SERS) spectroscopy of nucleic acids: from fundamental studies to real-life applications
Author: Garcia-Rico E, Alvarez-Puebla RA, Guerrini L.
ummary and discussion of the most recent cutting-edge research in the field of direct SERS sensing of nucleic acids.
Scissors become sensors
Author: Kocak DD, Gersbach CA.
The current studies greatly expand and diversify the possible beneficiaries of CRISPR technology, by developing a low-cost technique that has …
Next-generation diagnostics with CRISPR
Author: Chertow DS.
Chen et al. (3), Myhrvold et al. (4), and Gootenberg et al. (5), respectively, highlight how evolving insights into CRISPR-Cas …
Paper-Based Nucleic Acid Amplification Tests for Point-of-Care Diagnostics
Author: Kaur N, Toley BJ.
This article aims to review and analyse the current state of development of paper-based NAATs. We project paper-based NAATs as …
Molecular diagnosis of protozoan parasites by Recombinase Polymerase Amplification
Author: Castellanos-Gonzalez A, White A.C, Melby P, Travi B.
Among isothermal methods, recombinase polymerase amplification (RPA) is sensitive and potentially applicable at POC. We and others have developed RPA …
Simple Approaches to Minimally-Instrumented, Microfluidic-Based Point-of-Care Nucleic Acid Amplification Tests
Author: Mauk MG, Song J, Liu C, Bau HH.
Designs and applications of microfluidics-based devices for molecular diagnostics (Nucleic Acid Amplification Tests, NAATs) in infectious disease testing are reviewed, …
Infectious Pathogens Meet Point-of-Care Diagnostics
Author: Zarei M.
This review covers the developments on POC diagnosis of Zika, Ebola, Dengue, Malaria, HIV, Hepatitis, and Influenza between 2015 and …
Library preparation methods for next-generation sequencing: Tone down the bias
Author: Van Dijk EL, Jaszczyszyn Y, Thermes C.
Next-generation sequencing (NGS) has caused a revolution in biology. NGS requires the preparation of libraries in which (fragments of) DNA ..
Isothermal amplified detection of DNA and RNA
Author: Yan L, Zhou J, Zheng Y, Gamson AS, Roembke BT, Nakayama S, Sintim HO.
This review highlights various methods that can be used for a sensitive detection of nucleic acids without using thermal cycling …