Trichostatin A – A HDAC inhibitor

Trichostatin A – A HDAC inhibitor

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Catalog# 1606

Size: 1 mg

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Potent, reversible inhibitor of histone deacetylase. Mediates the activation of O6- methylguanine-DNA methyltransferase (MGMT). May be involved in cell cycle progression of several cell types, induces cell growth arrest at both G1 and G2/M phases. In some cases induces apoptosis.


Cat # +Size 1606-1
Size 1 mg
Alternate Name TSA, [R-(E,E)]-7-[4-(Dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide
Appearance White solid
CAS # 58880-19-6
Molecular Formula C₁₇H₂₂N₂O₃
Molecular Weight 302.4
Purity ≥99%
Solubility DMSO (20 mg/ml) or EtOH (2 mg/ml)
InChi InChI=1S/C17H22N2O3/c1-12(5-10-16(20)18-22)11-13(2)17(21)14-6-8-15(9-7-14)19(3)4/h5-11,13,22H,1-4H3,(H,18,20)/b10-5+,12-11+/t13-/m1/s1
PubChem CID 444732
MDL Number MFCD03848392
Handling Protect from air and moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.




Chen, S. et. al. Histone Deacetylase (HDAC) Activity Is Critical for Embryonic Kidney Gene Expression, Growth, and Differentiation. J. Biol. Chem., Sep 2011; 286: 32775 - 32789.

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