Catalog# 2323

Size: 50 mg

Price Not Available

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KEY FEATURES:• Amine-reactive; has a spacer with arm length of 22.4 Å which helps to minimize steric hindrance to biotin labeling• More water-soluble than the corresponding NHS compound without the sulfo group• Membrane-impermeable• Forms permanent amide bonds and the spacer arm cannot be cleavedAPPLICATIONS:• Sulfo-NHS-LC-Biotin is ideal for biotinylating antibody or protein that can then be used for protein detection, purification or immobilization • Sulfo-NHS-LC-Biotin is particularly useful for targeting cell surface proteins due to the membrane-impermeability of this reagent


SKU-Size2323-set (Size: 1 set (10 x 1 mg))
2323-50 (Size: 50 mg)
2323-100 (Size: 100 mg)
Alternate Name Sulfosuccinimidyl-2-(biotinamido)-ethyl-1,3'-dithiopropionate; Biotin disulfide N-Hydroxysulfosuccinimide ester
Appearance White to off-white solid
CAS # 325143-98-4
Molecular Formula C₁₉H₂₇O₉N₄S₄Na
Molecular Weight 606.69
Purity ≥80% by NMR
Solubility H₂O (~ 6 mg/ml)
InChi InChI=1S/C19H30N4O8S4.Na/c24-15(4-2-1-3-13-17-12(11-32-13)21-19(27)22-17)20-7-10-34-33-9-6-16(25)31-23-8-5-14(18(23)26)35(28,29)30;/h12-14,17H,1-11H2,(H,20,24)(H2,21,22,27)(H,28,29,30);/q;+1/p-1
PubChem CID
MDL Number MFCD00078533
Handling Protect from moisture
Storage Conditions 4 ̊C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


When a protein is biotinylated by Sulfo-NHS-LC-Biotin, which part of this molecule attached to protein?
Sulfo-NHS-LC-biotin (Sulfosuccinimidyl 6-(biotinamido) Hexanoate) is an amine-reactive biotinylation agent. It covalently binds to the amine groups in proteins and other molecules through its NHS ester forming an amide linkage.

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