Description
Taurodeoxycholic acid is a taurine-conjugated form of the secondary bile acid deoxycholic acid. Acts as a useful detergent for the solubilization of lipids and membrane–bound proteins. Taurodeoxycholic acid stimulates chloride ion secretion through calcium-activated chloride ion channels and cystic fibrosis transmembrane conductance regulator (CFTR) in Calu-3 airway epithelial cell monolayers when applied basolaterally.
Datasheet
| Cat # +Size | B3274-1G(Size: 1 g) B3274-5G(Size: 5 g) |
|---|---|
| Alternate Name | 2-[[(3α,5β,12α)-3,12-dihydroxy-24-oxocholan-24-yl]amino]-ethanesulfonic acid, monosodium salt Taurocholic acid sodium |
| Appearance | White to off-white solid |
| CAS # | 1180-95-6 |
| Molecular Formula | C₂₆H₄₄NNaO₆S |
| Molecular Weight | 522.69 |
| Purity | ≥97% |
| Solubility | C₂₆H₄₄NNaO₆S |
| SMILES | CC(CCC(=O)NCCS(=O)(=O)[O-])C1CCC2C1(C(CC3C2CCC4C3(CCC(C4)O)C)O)C.[Na+] |
| InChi | InChI=1S/C26H45NO6S.Na/c1-16(4-9-24(30)27-12-13-34(31,32)33)20-7-8-21-19-6-5-17-14-18(28)10-11-25(17,2)22(19)15-23(29)26(20,21)3;/h16-23,28-29H,4-15H2,1-3H3,(H,27,30)(H,31,32,33);/q;+1/p-1/t16-,17-,18-,19+,20-,21+,22+,23+,25+,26-;/m1./s1 |
| InChi Key | YXHRQQJFKOHLAP-FVCKGWAHSA-M |
| PubChem CID | 23664773 |
| MDL Number | MFCD00003671 |
| Handling | Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure. |
| Storage Conditions | -20ºC |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
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