Lithocholic acid


Lithocholic acid (LCA) is a hydrophobic secondary bile acid that is primarily formed in the intestine by the bacterial 7-α dehydroxylation of chenodeoxycholic acid. Acts as a detergent to solubilize fats for absorption. Known to display both carcinogenic and apoptotic activities. Also binds to the p53 binding sites of both MDM2 and MDM4 with a five-fold preference for MDM4.


Cat # +Size 2187-1G (Size: 1 g )
2187-5G (Size: 5g )
Alternate Name 3α-Hydroxy-5β-cholan-24-oic acid, 3α-Hydroxy-5β-cholanic acid, 5β-Cholan-24-oic acid-3α-ol; LCA
Appearance White to off-white solid
CAS # 434-13-9
Molecular Formula C₂₄H₄₀O₃
Molecular Weight 376.57
Purity ≥97% by TLC
Solubility DMSO or EtOH
InChi InChI=1S/C24H40O3/c1-15(4-9-22(26)27)19-7-8-20-18-6-5-16-14-17(25)10-12-23(16,2)21(18)11-13-24(19,20)3/h15-21,25H,4-14H2,1-3H3,(H,26,27)/t15-,16-,17-,18+,19-,20+,21+,23+,24-/m1/s1
PubChem CID 9903
MDL Number MFCD00003682
Handling Protect from air and moisture
Storage Conditions RT
Shipping Conditions RT
USAGE For Research Use Only! Not For Use in Humans.



We're here to help

Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

Contact Tech Support

High Quality Guaranteed Product

Our products such as Elisa, Antibodies, Proteins, Peptides and sequencing kits are covered by Biolinkk quality warranty and will work as described in datasheet, a free replacement or money back is guaranteed if does not perform according to datasheet.

Learn More