Lithocholic acid (LCA) is a hydrophobic secondary bile acid that is primarily formed in the intestine by the bacterial 7-α dehydroxylation of chenodeoxycholic acid. Acts as a detergent to solubilize fats for absorption. Known to display both carcinogenic and apoptotic activities. Also binds to the p53 binding sites of both MDM2 and MDM4 with a five-fold preference for MDM4.
|Cat # +Size||2187-1G (Size: 1 g )
2187-5G (Size: 5g )
|Alternate Name||3α-Hydroxy-5β-cholan-24-oic acid, 3α-Hydroxy-5β-cholanic acid, 5β-Cholan-24-oic acid-3α-ol; LCA|
|Appearance||White to off-white solid|
|Purity||≥97% by TLC|
|Solubility||DMSO or EtOH|
|Handling||Protect from air and moisture|
|USAGE||For Research Use Only! Not For Use in Humans.|
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