Description
Antibiotic that acts as a potent and selective calcium ionophore; more effective than A23187. Ionomycin binds Ca2+ in the 7.0-9.5 pH range with the resulting complex exhibiting intense UV absorption. Ionomycin induces apoptosis in immature B cell lines and in cultured embryonic rat cortical neurons. More mature B cell lines do not undergo apoptosis, but are arrested in the G1 phase of the cell cycle.
Datasheet
| Cat # +Size | 1565-1 (Size: 1 mg)
1565-5 (Size: 51 mg) |
| Alternate Name | - |
| Appearance | Waxy solid |
| CAS # | 56092-81-0 |
| Molecular Formula | C₄₁H₇₂O₉ |
| Molecular Weight | 709.02 |
| Purity | ≥97% |
| Solubility | DMSO |
| SMILES | CC(CCC(=O)O)CC(C)CC(C)C(=O)C=C(C(C)CC(C)CC=CC(C)C(C(C)C(CC1CCC(O1)(C)C2CCC(O2)(C)C(C)O)O)O)O |
| InChi | InChI=1S/C41H72O9/c1-25(21-29(5)34(43)24-35(44)30(6)22-27(3)20-26(2)14-15-38(46)47)12-11-13-28(4)39(48)31(7)36(45)23-33-16-18-41(10,49-33)37-17-19-40(9,50-37)32(8)42/h11,13,24-33,36-37,39,42-43,45,48H,12,14-23H2,1-10H3,(H,46,47)/b13-11+,34-24-/t25-,26-,27+,28-,29-,30+,31+,32-,33+,36+,37-,39-,40+,41+/m1/s1 |
| InChi Key | PGHMRUGBZOYCAA-ADZNBVRBSA-N|
| PubChem CID | 6912226 |
| MDL Number | MFCD06798385 |
| Handling | Protect from light and moisture |
| Storage Conditions | -20°C |
| Shipping Conditions | RT |
| USAGE | For Research Use Only! Not For Use in Humans. |
FAQ
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CITATIONS
Nadiya Byts. Transmembrane Prolyl 4-Hydroxylase is a Novel Regulator of Calcium Signaling in Astrocytes. eNeuro. Jan 2021. 33298456.
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