Hemocyanin-Keyhole Limpet (KLH) subunits, powder

Hemocyanin-Keyhole Limpet (KLH) subunits, powder

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Catalog# 6286

Size: 1 mg

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Hemocyanins are proteins that use copper binding sites to bind and transport oxygen in a variety of arthropods and mollusks. Hemocyanin is isolated from the hemolymph of the animals. Hemocyanin is one of the strongest antigens known. Hemocyanin has been in use as an immunological reagent for many years. It is used as a carrier protein for antibody production against antigens. Recent advances in immunology and the role immune system plays in diseases have opened a whole new era of product development activities aimed at developing novel therapeutics which is aimed at teaching the body's immune system to fight diseases like cancer, AIDS, etc. The approach involves the use of highly immunogenic molecule like the hemocyanin for non-specific immunostimulation (NSI) or active specific immunostimulation (ASI) using conjugate vaccines, wherein the tumor (disease) specific antigens are covalently bound to carrier protein like KLH and the product used in human clinical studies. Such products are termed “vaccines”. BioVision’s KLH subunits powder has major advantages associated with it, in terms of flexibility of use and the choice of buffer in early developmental studies. These subunits are highly pure and have low endotoxin content.


Cat # +Size 6286-1
Size 1 mg
Alternate Name KLH, keyhole limpett hemocyanin, hemocyanin, Megathura crenulata hemocyanin
Gene Symbol KLH
Source Megathura crenulata, Giant keyhole limpet
Appearance Lyophilized protein
Physical Form Description Freeze Dried
Molecular Weight 350 and 390 kDa (Two main characteristic bands co-migrating with ferritin)
Purity by SDS-PAGE ≥ 95%
Reconstitution Instructions Resuspend in sterile water to a 1 mg/ml concentration
Handling Centrifuge the vial prior to opening.
Storage Conditions 2-8°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans



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