Hemocyanins are proteins that use copper binding sites to bind and transport oxygen in a variety of arthropods and mollusks. Hemocyanin is isolated from the hemolymph of the animals. Hemocyanin is one of the strongest antigens known. Hemocyanin has been in use as an immunological reagent for many years. It is used as a carrier protein for antibody production against antigens. Recent advances in immunology and the role immune system plays in diseases have opened a whole new era of product development activities aimed at developing novel therapeutics which is aimed at teaching the body's immune system to fight diseases like cancer, AIDS, etc. The approach involves the use of highly immunogenic molecule like the hemocyanin for non-specific immunostimulation (NSI) or active specific immunostimulation (ASI) using conjugate vaccines, wherein the tumor (disease) specific antigens are covalently bound to carrier protein like KLH and the product used in human clinical studies. Such products are termed “vaccines”. BioVision’s KLH subunits powder has major advantages associated with it, in terms of flexibility of use, the choice of buffer in early developmental studies and avoidance of issues associated with reconstitution of dry powder. These subunits are highly pure and have low endotoxin content.
|Cat # +Size||6288-25|
|Alternate Name||KLH, keyhole limpett hemocyanin, hemocyanin, Megathura crenulata hemocyanin|
|Source||Megathura crenulata, Giant keyhole limpet|
|Physical Form Description||25 mg in phosphate buffered saline, pH 7.2, containing 1 mM calcium chloride and 0.5 mM magnesium chloride with 15 mM sodium azide as preservative. The liquid may appear faint blue to blue with some haziness due to particulates from the native source.|
|Molecular Weight||370 kDa (One major band)|
|Handling||Centrifuge the vial prior to opening.|
|Shipping Conditions||Gel Pack|
|USAGE||For Research Use Only! Not to be used in humans|
High Quality Guaranteed Product
Our products such as Elisa, Antibodies, Proteins, Peptides and sequencing kits are covered by Biolinkk quality warranty and will work as described in datasheet, a free replacement or money back is guaranteed if does not perform according to datasheet.