Geldanamycin – A Hsp90 inhibito


Catalog# 1564

Size: 1 mg


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Description




A potent antitumor antibiotic . Binds specifically to heat shock protein HSP90 and its GP96 homologue; inhibits protein maturation.


Datasheet




QTQAWLPCGQOSGP-KSRBKZBZSA-N
Cat # +Size 1564-1 (Size: 1 mg)
1564-5 (Size: 51 mg)
Size 5 mg
Alternate NameGeldanomycin; U-29135
Appearance Yellow to orange solid
CAS # 30562-34-6
Molecular Formula C₂₉H₄₀N₂O₉
Molecular Weight 560.64
Purity ≥99%
SolubilityDMSO
SMILESCC1CC(C(C(C=C(C(C(C=CC=C(C(=O)NC2=CC(=O)C(=C(C1)C2=O)OC)C)OC)OC(=O)N)C)C)O)OC
InChi InChI=1S/C29H40N2O9/c1-15-11-19-25(34)20(14-21(32)27(19)39-7)31-28(35)16(2)9-8-10-22(37-5)26(40-29(30)36)18(4)13-17(3)24(33)23(12-15)38-6/h8-10,13-15,17,22-24,26,33H,11-12H2,1-7H3,(H2,30,36)(H,31,35)/b10-8-,16-9+,18-13+/t15-,17+,22+,23+,24-,26+/m1/s1
InChi Key
PubChem CID 5288382
MDL NumberMFCD00274570
Handling Protect from light and moisture
Storage Conditions-20°C
Shipping ConditionsGel Pack
USAGE For Research Use Only! Not For Use in Humans.




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