Geldanamycin – A Hsp90 inhibito
Datasheet (PDF) | Safety Data Sheets (MSDS)(PDF)
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Description
A potent antitumor antibiotic . Binds specifically to heat shock protein HSP90 and its GP96 homologue; inhibits protein maturation.
Datasheet
Cat # +Size | 1564-1 (Size: 1 mg)
1564-5 (Size: 51 mg) |
Size | 5 mg |
Alternate Name | Geldanomycin; U-29135 |
Appearance | Yellow to orange solid |
CAS # | 30562-34-6 |
Molecular Formula | C₂₉H₄₀N₂O₉ |
Molecular Weight | 560.64 |
Purity | ≥99% |
Solubility | DMSO |
SMILES | CC1CC(C(C(C=C(C(C(C=CC=C(C(=O)NC2=CC(=O)C(=C(C1)C2=O)OC)C)OC)OC(=O)N)C)C)O)OC |
InChi | InChI=1S/C29H40N2O9/c1-15-11-19-25(34)20(14-21(32)27(19)39-7)31-28(35)16(2)9-8-10-22(37-5)26(40-29(30)36)18(4)13-17(3)24(33)23(12-15)38-6/h8-10,13-15,17,22-24,26,33H,11-12H2,1-7H3,(H2,30,36)(H,31,35)/b10-8-,16-9+,18-13+/t15-,17+,22+,23+,24-,26+/m1/s1 |
InChi Key | QTQAWLPCGQOSGP-KSRBKZBZSA-N|
PubChem CID | 5288382 |
MDL Number | MFCD00274570 |
Handling | Protect from light and moisture |
Storage Conditions | -20°C |
Shipping Conditions | Gel Pack |
USAGE | For Research Use Only! Not For Use in Humans. |
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