Doxorubicin.HCl – Anti-tumor antibiotic


Doxorubicin.HCl – Anti-tumor antibiotic


Datasheet (PDF)   |   Safety Data Sheets (MSDS)(PDF)

View All Related Products


Catalog# 1527

Size: 5 mg


Price Not Available

Contact Us




Description




Anti-tumor antibiotic. Inhibitor of Reverse transcriptase and RNA Polymerase. Immunosuppressive agent. Highly effective myotoxin that inhibits topoisomerase II. Binds to Nucleic acids, presumably by specific intercalation into the DNA double helix, thereby inhibiting necleic acid synthesis. Induces apoptosis.


Datasheet




Cat # +Size 1527-5
Size 5 mg
Alternate NameAdriamycin® hydrochloride, DOX, Hydroxydaunorubicin hydrochloride
Appearance Orange-red powder
CAS # 25316-40-9
Molecular Formula C₂₇H₂₉NO₁₁ .HCl
Molecular Weight 579.98
Purity >98% by TLC
SolubilityH₂O
SMILESCC1C(C(CC(O1)OC2CC(CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)CO)O)N)O.Cl
InChi InChI=1S/C27H29NO11.ClH/c1-10-22(31)13(28)6-17(38-10)39-15-8-27(36,16(30)9-29)7-12-19(15)26(35)21-20(24(12)33)23(32)11-4-3-5-14(37-2)18(11)25(21)34;/h3-5,10,13,15,17,22,29,31,33,35-36H,6-9,28H2,1-2H3;1H/t10-,13-,15-,17-,22+,27-;/m0./s1
InChi KeyMWWSFMDVAYGXBV-RUELKSSGSA-N
PubChem CID 443939
MDL NumberMFCD00077757
Handling Protect from moisture
Storage Conditions 4°C
Shipping ConditionsRT
USAGE For Research Use Only! Not For Use in Humans.




FAQ



-

CITATIONS Katoh S-Y et al. J. Biochem 143: 517 - 524.










We're here to help


Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.


Contact Tech Support







High Quality Guaranteed Product


Our products such as Elisa, Antibodies, Proteins, Peptides and sequencing kits are covered by Biolinkk quality warranty and will work as described in datasheet, a free replacement or money back is guaranteed if does not perform according to datasheet.


Learn More