Cholesteryl hemisuccinate is a useful cholesterol-based detergent that increases the stability of G protein-coupled receptors (GPCRs). Together with mutagenesis studies and recent GPCR structures, it has been determined that stabilization is attained through a combination of specific sterol binding to GPCRs and modulation of micelle morphology.
|SKU-Size|| B1978-1G (Size: 1 g) |
B1978-5G (Size: 5 g)
|Alternate Name||3β-Hydroxy-5-cholestene 3-hemisuccinate; 5-Cholesten-3β-ol 3-hemisuccinate; CHS|
|Appearance||White to off-white solid|
|Solubility||EtOH (warm; with faint turbidity)|
|Handling||Protect from air and moisture|
|Shipping Conditions||Gel Pack|
|USAGE||For Research Use Only! Not For Use in Humans.|
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