Description
Chenodeoxycholic acid (CDCA) is a hydrophobic primary bile acid that activates nuclear receptors involved in cholesterol metabolism. EC50 concentrations for activation of FXR (farnesoid X receptor) range from 13-34 μM. In cells, CDCA also binds to bile acid binding proteins (BABP) with a reported stoichiometery of 1:2.
Datasheet
| SKU-Size | 2831-1G (Size: 1 g) 2831-5G (Size: 5 g) 2831-25G (Size: 25 g) |
| Alternate Name | CDCA; Fluibil; Hekbilin; Anthropodeoxycholic Acid; Kebilis; Ulmenide |
|---|---|
| Appearance | White to off-white solid |
| CAS # | 474-25-9 |
| Molecular Formula | C₂₄H₄₀O₄ |
| Molecular Weight | 392.57 |
| Purity | ≥95% |
| Solubility | EtOH (50 mg/ml) |
| SMILES | CC(CCC(=O)O)C1CCC2C1(CCC3C2C(CC4C3(CCC(C4)O)C)O)C |
| InChi | C[C@H](CCC(=O)O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2[C@@H](C[C@H]4[C@@]3(CC[C@H](C4)O)C)O)C |
| InChi Key | RUDATBOHQWOJDD-BSWAIDMHSA-N |
| PubChem CID | 10133 |
| MDL Number | MFCD00064142 |
| Handling | Hygroscopic |
| Storage Conditions | -20°C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
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