Brefeldin A – Disruptor of Golgi apparatus


Brefeldin A – Disruptor of Golgi apparatus


Datasheet (PDF)   |   Safety Data Sheets (MSDS)(PDF)

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Catalog# 1560

Size: 5 mg


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Description




Brefeldin A has been shown to induce apoptosis in human tumor cells through caspase activation. It has also been shown to block translocation of proteins from the endoplasmic reticulum to the Golgi apparatus.


Datasheet




Cat # +Size 1560-5 ( Size: 5 mg )
1560-50 ( Size: 50 mg )
Alternate NameAscotoxin, BFA, Cyanein, Decumbin, γ,4-Dihydroxy-2-(6-hydroxy-1-heptenyl)-4-cyclopentanecrotonic acid λ-lactone
Appearance White solid
CAS # 20350-15-6
Molecular Formula C₁₆H₂₄O₄
Molecular Weight 280.36/td>
Purity ≥99%
SolubilityDMSO or EtOH (10 mg/ml)
SMILES CC1CCCC=CC2CC(CC2C(C=CC(=O)O1)O)O
InChi InChI=1S/C16H24O4/c1-11-5-3-2-4-6-12-9-13(17)10-14(12)15(18)7-8-16(19)20-11/h4,6-8,11-15,17-18H,2-3,5,9-10H2,1H3
InChi KeyKQNZDYYTLMIZCT-UHFFFAOYSA-N
PubChem CID 2430
MDL NumberMFCD12913297
Handling Protect from light and moisture
Storage Conditions -20°C
Shipping Conditions RT
USAGE For Research Use Only! Not For Use in Humans.




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CITATIONS

Andrew S. Nelson, Oral therapy with colonization factor antigen I prevents development of type 1 diabetes in Non-obese Diabetic mice. Sci Rep., Apr. 2020; 32273533.










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