The Quick-RNA 96 Kit is designed for the easy, reliable, and rapid isolation of DNA-free RNA from a wide range of cell (up to 10⁶) and tissue samples (up to 5 mg). The procedure combines a unique buffer system with Zymo-Spin™ plate technology to yield high quality total RNA (including small RNAs ~17-200 nt) in about 30 minutes. The procedure is simple: Add the provided RNA Lysis Buffer to a sample, then purify the RNA using the provided Silicon-A Plate. The result is highly-concentrated, DNA-free RNA that is suitable for subsequent RNA-based methods including RT-PCR, hybridization, sequencing etc.