Full Product Name:

Chitinase-3-Like Protein 1

Catalog No.:

BL0062E

Size:

48T,96T

Detaction Range:

1-300ng/ml

Sensitivity:

0.52ng/ml

Sample Type:

Serum, plasma, cell culture supernates

Assay Type:

Sandwich

Species:

Bovine

Storage:

2-8ºC

Assay Time:

1h 30m

Background:

Carbohydrate-binding lectin with a preference for chitin. Has no chitinase activity. May play a role in tissue remodeling and in the capacity of cells to respond to and cope with changes in their environment. Plays a role in T-helper cell type 2 (Th2) inflammatory response and IL-13-induced inflammation, regulating allergen sensitization, inflammatory cell apoptosis, dendritic cell accumulation and M2 macrophage differentiation. Facilitates invasion of pathogenic enteric bacteria into colonic mucosa and lymphoid organs. Mediates activation of AKT1 signaling pathway and subsequent IL8 production in colonic epithelial cells. Regulates antibacterial responses in lung by contributing to macrophage bacterial killing, controlling bacterial dissemination and augmenting host tolerance. Also regulates hyperoxia-induced injury, inflammation and epithelial apoptosis in lung (By similarity).

UniProt:

P30922

MASS（Da）:

43,032

GeneID:

286869

Synonyms:

39 kDa whey protein;Cartilage glycoprotein 39;CGP-39;CHI3L1;Chitinase-3-like protein 1;Chitinase-like protein 1;CLP-1;GP-39;Signal-processing protein;SPC-40

Gene Names:

CHI3L1

Research Area:

Others

Target Protein:

CHI3L1