Full Product Name:

Angiopoietin-Like Protein 4

Catalog No.:

BL0042E

Size:

96T, 48T

Detaction Range:

1-310ng/ml

Sensitivity:

0.45ng/ml

Sample Type:

Serum, plasma, cell culture supernates

Assay Type:

Sandwich

Species:

Bovine

Storage:

2-8ºC

Assay Time:

1h 30m

Background:

Mediates inactivation of the lipoprotein lipase LPL, and thereby plays a role in the regulation of triglyceride clearance from the blood serum and in lipid metabolism. May also play a role in regulating glucose homeostasis and insulin sensitivity. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage (By similarity). Upon heterologous expression, inhibits the adhesion of endothelial cell to the extracellular matrix (ECM), and inhibits the reorganization of the actin cytoskeleton, formation of actin stress fibers and focal adhesions in endothelial cells that have adhered to ANGPTL4-containing ECM (in vitro) (By similarity). Depending on context, may modulate tumor-related angiogenesis (By similarity). [ANGPTL4 N-terminal chain]: Mediates inactivation of the lipoprotein lipase LPL, and thereby plays an important role in the regulation of triglyceride clearance from the blood serum and in lipid metabolism. Has higher activity in LPL inactivation than the uncleaved protein.

UniProt:

Q2KJ51

MASS（Da）:

45,553

GeneID:

509963

Synonyms:

Angiopoietin-like protein 4;Angiopoietin-related protein 4;ANGPTL 4;ANGPTL4;ANGPTL4 C-terminal chain;ANGPTL4 N-terminal chain

Gene Names:

ANGPTL4

Research Area:

Cardiovascular; Cancer; Metabolism

Target Protein:

ANGPTL4