Unc18-3 Polyclonal Antibody
- Size: 100ul
- Application: ELISA, IHC-P, IHC-F, IF(IHC-P), IF(IHC-F), IF(ICC)
- Reactivity:
- Predicted Reactivity: Human, Mouse, Rat, Dog, Cow, Pig, Rabbit
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PRODUCT DETAILS
SPECIFICATIONS |
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PRODUCT NAME |
Unc18-3 Polyclonal Antibody |
CONJUGATION |
Unconjugated |
HOST |
Rabbit |
SOURCE |
KLH conjugated synthetic peptide derived from human Unc18-3 |
IMMUNOGEN RANGE |
165-260/592 |
CLONALITY |
Polyclonal |
ISOTYPE |
IgG |
CONCENTRATION |
1ug/ul |
PURIFICATION |
Purified by Protein A. |
STORAGE BUFFER |
Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. |
STORAGE CONDITION |
Store at -20°C for 12 months.. |
TARGET |
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GENE ID |
|
SUBCELLULAR LOCATION |
Cytoplasm, Cell membrane |
SYNONYMS |
Munc 18 3; Munc18 3; Munc 18-3; Protein unc-18 homolog 3; STXB3_HUMAN. |
BACKGROUND |
May participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. Essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. Can interact with syntaxins 1, 2, and 3 but not syntaxin 4. May play a role in determining the specificity of intracellular fusion reactions. |
APPLICATION DILUTION |
ELISA(1:500-1000), IHC-P(1:200-400), IHC-F(1:100-500), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200) |