UBE2M Polyclonal Antibody


UBE2M Polyclonal Antibody

  • Size: 100ul
  • Application: WB, ELISA, IHC-P, IHC-F, IF(IHC-P), IF(IHC-F), IF(ICC)
  • Reactivity: Xenopus laevis
  • Predicted Reactivity: Human, Mouse, Rat, Cow, Horse

  • Datasheet      Tech Support


Catalog# bs-8382R

Size:100ul Datasheet


 SizePrice
 100ul ₹ 40479

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PRODUCT DETAILS






SPECIFICATIONS

PRODUCT NAME

UBE2M Polyclonal Antibody

CONJUGATION

Unconjugated

HOST

Rabbit

SOURCE

KLH conjugated synthetic peptide derived from human UBE2M

IMMUNOGEN RANGE

1-100/183

CLONALITY

Polyclonal

ISOTYPE

IgG

CONCENTRATION

1ug/ul

PURIFICATION

Purified by Protein A.

STORAGE BUFFER

Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide.

STORAGE CONDITION

Store at -20°C for 12 months..


TARGET

GENE ID

9040

SUBCELLULAR LOCATION

Cytoplasm, Nucleus, Secreted, Extracellular matrix

SYNONYMS

hUbc12; NEDD8 carrier protein; NEDD8 conjugating enzyme Ubc12; NEDD8 protein ligase; NEDD8-conjugating enzyme Ubc12; UBC-RS2; UBC12; UBC12_HUMAN; ube2m; ubiquitin carrier protein M; Ubiquitin conjugating enzyme E2 M; Ubiquitin-conjugating enzyme E2 M; ubiquitin-protein ligase M; yeast UBC12 homolog.

BACKGROUND

Accepts the ubiquitin-like protein NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX1, but not RBX2, suggests that the RBX1-UBE2M complex neddylates specific target proteins, such as CUL1, CUL2, CUL3 and CUL4. Involved in cell proliferation.

APPLICATION DILUTION

WB(1:300-1000), ELISA(1:500-1000), IHC-P(1:200-400), IHC-F(1:100-500), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)












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