UBE2M Polyclonal Antibody, Cy3 Conjugated
- Size: 100ul
- Application: IF(IHC-P), IF(IHC-F), IF(ICC)
- Reactivity: Xenopus laevis
- Predicted Reactivity: Human, Mouse, Rat, Cow, Horse
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PRODUCT DETAILS
SPECIFICATIONS |
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PRODUCT NAME |
UBE2M Polyclonal Antibody, Cy3 Conjugated |
CONJUGATION |
Cy3 |
HOST |
Rabbit |
SOURCE |
KLH conjugated synthetic peptide derived from human UBE2M |
IMMUNOGEN RANGE |
1-100/183 |
CLONALITY |
Polyclonal |
ISOTYPE |
IgG |
CONCENTRATION |
1ug/ul |
PURIFICATION |
Purified by Protein A. |
STORAGE BUFFER |
Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. |
STORAGE CONDITION |
Store at 4°C for 12 months. |
TARGET |
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GENE ID |
|
SUBCELLULAR LOCATION |
Cytoplasm, Nucleus, Secreted, Extracellular matrix |
SYNONYMS |
hUbc12; NEDD8 carrier protein; NEDD8 conjugating enzyme Ubc12; NEDD8 protein ligase; NEDD8-conjugating enzyme Ubc12; UBC-RS2; UBC12; UBC12_HUMAN; ube2m; ubiquitin carrier protein M; Ubiquitin conjugating enzyme E2 M; Ubiquitin-conjugating enzyme E2 M; ubiquitin-protein ligase M; yeast UBC12 homolog. |
BACKGROUND |
Accepts the ubiquitin-like protein NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX1, but not RBX2, suggests that the RBX1-UBE2M complex neddylates specific target proteins, such as CUL1, CUL2, CUL3 and CUL4. Involved in cell proliferation. |
APPLICATION DILUTION |
IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200) |