SW480 lysates probed with TESPA1 Polyclonal Antibody, Unconjugated (bs-8623R) at 1:300 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at 1:10000 for 60 min at 37°C.
PRODUCT DETAILS
SPECIFICATIONS
PRODUCT NAME
TESPA1 Polyclonal Antibody
CONJUGATION
Unconjugated
HOST
Rabbit
SOURCE
KLH conjugated synthetic peptide derived from human TESPA1
IMMUNOGEN RANGE
231-330/521
CLONALITY
Polyclonal
ISOTYPE
IgG
CONCENTRATION
1ug/ul
PURIFICATION
Purified by Protein A.
STORAGE BUFFER
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Protein TESPA1; TESPA1; Thymocyte-expressed positive selection-associated protein 1; KIAA0748; HSPC257
BACKGROUND
Required for the development and maturation of T-cells, its function being essential for the late stages of thymocyte development (By similarity). Plays a role in T-cell antigen receptor (TCR)-mediated activation of the ERK and NFAT signaling pathways, possibly by serving as a scaffolding protein that promotes the assembly of the LAT signalosome in thymocytes. May play a role in the regulation of inositol 1,4,5-trisphosphate receptor-mediated Ca2+ release and mitochondrial Ca2+ uptake via the mitochondria-associated endoplasmic reticulum membrane (MAM) compartment.
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