LSD2 / AOF1 Polyclonal Antibody, ALEXA FLUOR¨ 680 Conjugated


LSD2 / AOF1 Polyclonal Antibody, ALEXA FLUOR¨ 680 Conjugated

  • Size: 100ul
  • Application: IF(IHC-P), IF(IHC-F), IF(ICC)
  • Reactivity: Mouse, Rat
  • Predicted Reactivity: Human, Dog, Cow, Sheep, Pig, Horse, Rabbit

  • Datasheet      Tech Support


Catalog# bs-7415R-A680

Size:100ul Datasheet


 SizePrice
 100ul ₹ 44220

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PRODUCT DETAILS






SPECIFICATIONS

PRODUCT NAME

LSD2 / AOF1 Polyclonal Antibody, ALEXA FLUOR¨ 680 Conjugated

CONJUGATION

ALEXA FLUOR¨ 680

HOST

Rabbit

SOURCE

KLH conjugated synthetic peptide derived from human LSD2 / AOF1

IMMUNOGEN RANGE

51-150/822

CLONALITY

Polyclonal

ISOTYPE

IgG

CONCENTRATION

1ug/ul

PURIFICATION

Purified by Protein A.

STORAGE BUFFER

Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide.

STORAGE CONDITION

Store at 4°C for 12 months.


TARGET

GENE ID

221656

SUBCELLULAR LOCATION

Nucleus

SYNONYMS

LSD2 / AOF1; KDM1B; amine oxidase (flavin containing) domain 1; amine oxidase, flavin containing 1; AOF1; bA204B7.3; C6orf193; dJ298J15.2; Flavin-containing amine oxidase domain-containing protein 1; FLJ33898; FLJ34109; FLJ43328; KDM1B; KDM1B_HUMAN; LSD2; lysine (K)-specific demethylase 1B; Lysine-specific demethylase 2; Lysine-specific histone demethylase 1B; Lysine-specific histone demethylase 2.

BACKGROUND

Histone demethylase that demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. Required for de novo DNA methylation of a subset of imprinted genes during oogenesis. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Demethylates both mono- and di-methylated 'Lys-4' of histone H3. Has no effect on tri-methylated 'Lys-4', mono-, di- or tri-methylated 'Lys-9', mono-, di- or tri-methylated 'Lys-27', mono-, di- or tri-methylated 'Lys-36' of histone H3, or on mono-, di- or tri-methylated 'Lys-20' of histone H4.

APPLICATION DILUTION

IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)












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