Lin28A/B Polyclonal Antibody, ALEXA FLUOR¨ 750 Conjugated
- Size: 100ul
- Application: IF(IHC-P), IF(IHC-F), IF(ICC)
- Reactivity: Human, Mouse, Rat
- Predicted Reactivity: Cow, Sheep, Pig, Horse, Rabbit
-
Datasheet
Tech Support
PRODUCT DETAILS
SPECIFICATIONS |
|
|---|---|
|
PRODUCT NAME |
Lin28A/B Polyclonal Antibody, ALEXA FLUOR¨ 750 Conjugated |
|
CONJUGATION |
ALEXA FLUOR¨ 750 |
|
HOST |
Rabbit |
| SOURCE |
KLH conjugated synthetic peptide derived from human Lin28A |
| IMMUNOGEN RANGE |
75-180/209 |
| CLONALITY |
Polyclonal |
| ISOTYPE |
IgG |
| CONCENTRATION |
1ug/ul |
| PURIFICATION |
Purified by Protein A. |
| STORAGE BUFFER |
Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. |
| STORAGE CONDITION |
Store at 4°C for 12 months. |
TARGET |
|
|---|---|
| GENE ID |
|
| SUBCELLULAR LOCATION |
Cytoplasm, Nucleus |
| SYNONYMS |
Protein lin-28 homolog A; LIN28A; Lin-28A; Zinc finger CCHC domain-containing protein 1; CSDD1; LIN28; ZCCHC1; Protein lin-28 homolog B; LIN28B; Lin-28B; CSDD2 |
| BACKGROUND |
LIN-28 is a highly conserved, RNA-binding, cytoplasmic protein. It consists of a cold shock domain and retroviral-type (CCHC) zinc finger motifs that were first identified in Caenorhabditis elegans. LIN-28 controls the timing of events during embryonic development and is readily expressed in embryos, embryonic stem cells and embryonal carcinoma cells. The presence of LIN-28 persists in some adult tissues including cardiac and skeletal muscle. In differentiating myoblasts, LIN-28 increases protein synthesis efficiency and binds to the growth and differentiation factor IGF-II. |
| APPLICATION DILUTION |
IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200) |
