KCNN4 Polyclonal Antibody
- Size: 100ul
- Application: WB, ELISA, IHC-P, IHC-F, IF(IHC-P), IF(IHC-F), IF(ICC)
- Reactivity: Human, Rat
- Predicted Reactivity: Mouse, Dog, Cow, Sheep, Pig, Horse, Rabbit, Guinea Pig
-
Datasheet
Tech Support
IMAGES
Lane 1: rat brain lysates Lane 2: rat heart lysates probed with Anti KCNN4 Polyclonal Antibody, Unconjugated (bs-6675R) at 1:200 in 4°C. Followed by conjugation to secondary antibody (bs-0295G-HRP) at 1:3000 90min in 37°C. Predicted band 50kD. Observed band size: 45kD, 50kD.
Formalin-fixed and paraffin embedded rat brain labeled with Anti KCNN4 Polyclonal Antibody, Unconjugated (bs-6675R) at 1:200 followed by conjugation to the secondary antibody and DAB staining
PRODUCT DETAILS
SPECIFICATIONS |
|
|---|---|
|
PRODUCT NAME |
KCNN4 Polyclonal Antibody |
|
CONJUGATION |
Unconjugated |
|
HOST |
Rabbit |
| SOURCE |
KLH conjugated synthetic peptide derived from human KCNN4 |
| IMMUNOGEN RANGE |
325-427/427 |
| CLONALITY |
Polyclonal |
| ISOTYPE |
IgG |
| CONCENTRATION |
1ug/ul |
| PURIFICATION |
Purified by Protein A. |
| STORAGE BUFFER |
Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. |
| STORAGE CONDITION |
Store at -20°C for 12 months.. |
TARGET |
|
|---|---|
| GENE ID |
|
| SUBCELLULAR LOCATION |
Cell membrane |
| SYNONYMS |
IK1; SK4; KCA4; hSK4; IKCA1; hKCa4; KCa3.1; hIKCa1; Intermediate conductance calcium-activated potassium channel protein 4; SKCa 4; SKCa4; Putative Gardos channel; KCNN4 |
| BACKGROUND |
Forms a voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization which promotes calcium influx. Required for maximal calcium influx and proliferation during the reactivation of naive T-cells. The channel is blocked by clotrimazole and charybdotoxin but is insensitive to apamin. |
| APPLICATION DILUTION |
WB(1:300-1000), ELISA(1:500-1000), IHC-P(1:200-400), IHC-F(1:100-500), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200) |
