Frizzled 7 Polyclonal Antibody, Cy3 Conjugated


Frizzled 7 Polyclonal Antibody, Cy3 Conjugated

  • Size: 100ul
  • Application: FCM, IF(IHC-P), IF(IHC-F), IF(ICC)
  • Reactivity: Human, Mouse, Rat
  • Predicted Reactivity: Dog, Cow, Pig, Chicken, Guinea Pig

  • Datasheet      Tech Support


Catalog# bs-5125R-Cy3

Size:100ul Datasheet


 SizePrice
 100ul ₹ 44220

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PRODUCT DETAILS






SPECIFICATIONS

PRODUCT NAME

Frizzled 7 Polyclonal Antibody, Cy3 Conjugated

CONJUGATION

Cy3

HOST

Rabbit

SOURCE

KLH conjugated synthetic peptide derived from human Frizzled 7

IMMUNOGEN RANGE

501-574/574

CLONALITY

Polyclonal

ISOTYPE

IgG

CONCENTRATION

1ug/ul

PURIFICATION

Purified by Protein A.

STORAGE BUFFER

Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide.

STORAGE CONDITION

Store at 4°C for 12 months.


TARGET

GENE ID

8324

SUBCELLULAR LOCATION

Cell membrane

SYNONYMS

FzE3; Frizzled-7; Fz-7; hFz7; FZD7

BACKGROUND

Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.

APPLICATION DILUTION

FCM(1:20-100), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)












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