Cytochrome C (6B10) Monoclonal Antibody, ALEXA FLUOR¨ 680 Conjugated
- Size: 100ul
- Application: IF(IHC-P)
- Reactivity: Human, Rat, Rabbit
- Predicted Reactivity:
-
Datasheet
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PRODUCT DETAILS
SPECIFICATIONS |
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PRODUCT NAME |
Cytochrome C (6B10) Monoclonal Antibody, ALEXA FLUOR¨ 680 Conjugated |
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CONJUGATION |
ALEXA FLUOR¨ 680 |
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HOST |
Mouse |
| SOURCE |
Recombinant human Cytochrome C Protein |
| IMMUNOGEN RANGE |
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| CLONALITY |
Monoclonal |
| ISOTYPE |
IgG |
| CONCENTRATION |
1ug/ul |
| PURIFICATION |
Purified by Protein A. |
| STORAGE BUFFER |
Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. |
| STORAGE CONDITION |
Store at 4°C for 12 months. |
TARGET |
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| GENE ID |
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| SUBCELLULAR LOCATION |
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| SYNONYMS |
Cytochrome c; CYCS |
| BACKGROUND |
Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases. |
| APPLICATION DILUTION |
IF(IHC-P)(1:50-200) |
