COMMD7 Polyclonal Antibody


COMMD7 Polyclonal Antibody

  • Size: 100ul
  • Application: ELISA, IHC-P, IHC-F, IF(IHC-P), IF(IHC-F), IF(ICC)
  • Reactivity:
  • Predicted Reactivity: Human, Mouse, Rat, Dog, Pig

  • Datasheet      Tech Support


Catalog# bs-8036R

Size:100ul Datasheet


 SizePrice
 100ul ₹ 33990

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PRODUCT DETAILS






SPECIFICATIONS

PRODUCT NAME

COMMD7 Polyclonal Antibody

CONJUGATION

Unconjugated

HOST

Rabbit

SOURCE

KLH conjugated synthetic peptide derived from human COMMD7

IMMUNOGEN RANGE

81-170/200

CLONALITY

Polyclonal

ISOTYPE

IgG

CONCENTRATION

1ug/ul

PURIFICATION

Purified by Protein A.

STORAGE BUFFER

Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide.

STORAGE CONDITION

Store at -20°C for 12 months..


TARGET

GENE ID

149951

SUBCELLULAR LOCATION

Cytoplasm, Nucleus, Secreted, Extracellular matrix

SYNONYMS

C20orf92; Chromosome 20 open reading frame 92; COMM domain containing 7; COMM domain containing protein 7; COMMD 7; dJ1085F17.3; FLJ14987; MGC33315; OTTHUMP00000030609; COMD7_HUMAN.

BACKGROUND

COMMD is a new family of proteins with homology to MURR1, a multifunctional protein that inhibits NFkB. These proteins form multimeric complexes and were identified in a biochemical screen for MURR1-associated factors. The family is defined by the presence of a conserved and unique motif termed the COMM (copper metabolism gene MURR1) domain, which functions as an interface for protein-protein interactions. The prototype of this family, MURR1/COMMD1, suppresses NFkB by affecting the association of NF-kappaB with chromatin. COMMD7 (COMM domain-containing protein 7) interacts with COMMD1 via its COMM domain. It also associates with the NF-kappa-B complex and suppresses its transcriptional activity.

APPLICATION DILUTION

ELISA(1:500-1000), IHC-P(1:200-400), IHC-F(1:100-500), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)












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