CDKN1A (Thr145) Polyclonal Antibody, Cy7 Conjugated


CDKN1A (Thr145) Polyclonal Antibody, Cy7 Conjugated

  • Size: 100ul
  • Application: FCM, IF(IHC-P), IF(IHC-F), IF(ICC)
  • Reactivity: Human, Mouse, Rat
  • Predicted Reactivity:

  • Datasheet      Tech Support


Catalog# bs-5237R-Cy7

Size:100ul Datasheet


 SizePrice
 100ul ₹ 44220

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PRODUCT DETAILS






SPECIFICATIONS

PRODUCT NAME

CDKN1A (Thr145) Polyclonal Antibody, Cy7 Conjugated

CONJUGATION

Cy7

HOST

Rabbit

SOURCE

KLH conjugated synthetic phosphopeptide derived from human CDKN1A around the phosphorylation site of Thr145 [RQ(p-T)S]

IMMUNOGEN RANGE

CLONALITY

Polyclonal

ISOTYPE

IgG

CONCENTRATION

1ug/ul

PURIFICATION

Purified by Protein A.

STORAGE BUFFER

Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide.

STORAGE CONDITION

Store at 4°C for 12 months.


TARGET

GENE ID

1026

SUBCELLULAR LOCATION

Cytoplasm, Nucleus

SYNONYMS

P21; CIP1; SDI1; WAF1; CAP20; CDKN1; MDA-6; p21CIP1; Cyclin-dependent kinase inhibitor 1; CDK-interacting protein 1; Melanoma differentiation-associated protein 6; CDKN1A; MDA6; PIC1

BACKGROUND

May be the important intermediate by which p53/TP53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression. Functions in the nuclear localization and assembly of cyclin D-CDK4 complex and promotes its kinase activity towards RB1. At higher stoichiometric ratios, inhibits the kinase activity of the cyclin D-CDK4 complex.

APPLICATION DILUTION

FCM(1:20-100), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)












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