PRODUCT NAME

CAMK2 beta Monoclonal Antibody, HRP Conjugated

CONJUGATION

HRP

HOST

Mouse

SOURCE

Recombinant human CAMK2 between 1-503 amino acids.

IMMUNOGEN RANGE

CLONALITY

Monoclonal

ISOTYPE

IgG1

CONCENTRATION

1ug/ul

PURIFICATION

STORAGE BUFFER

Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% Gentamicin.

STORAGE CONDITION

Store at 4°C for 12 months.

GENE ID

816

SUBCELLULAR LOCATION

Cytoplasm, Cell membrane

SYNONYMS

Calcium/calmodulin dependent protein kinase (CaM kinase) II beta; Calcium/calmodulin dependent protein kinase II beta; Calcium/calmodulin dependent protein kinase IIB; Calcium/calmodulin dependent protein kinase type II beta chain; calcium/calmodulin-dependent protein kinase II beta; Calcium/calmodulin-dependent protein kinase type II subunit beta; CAM 2; CaM kinase II beta chain; CaM kinase II beta subunit; CaM kinase II subunit beta; CaM-kinase II beta chain; CAM2; CAMK 2; CAMK 2B; CaMK II beta subunit; CaMK II subunit beta; CaMK-II subunit beta; CAMK2; Camk2b; CAMKB; CaMKII beta subunit; CaMKIIB; KCC2B_HUMAN; MGC29528; Proline rich calmodulin dependent protein kinase; proline rich calmodulin-dependent protein kinase;

BACKGROUND

Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca(2+)/calmodulin-binding and autophosphorylation, and is involved in sarcoplamic reticulum Ca(2+) transport in skeletal muscle and may function in dendritic spine and synapse formation and neuronal plasticity. In slow-twitch muscles, is involved in regulation of sarcoplamic reticulum (SR) Ca(2+) transport and in fast-twitch muscle participates in the control of Ca(2+) release from the SR through phosphorylation of the ryanodine receptor-coupling factor triadin. In neurons, may participate in the promotion of dendritic spine and synapse formation and maintenance of synaptic plasticity which enables long-term potentiation (LTP) and hippocampus-dependent learning.

APPLICATION DILUTION

WB(1:300-1000), IHC-P(1:200-400)