ANKS1B Polyclonal Antibody, Cy5 Conjugated
- Size: 100ul
- Application: IF(IHC-P)
- Reactivity: Human, Mouse, Rat
- Predicted Reactivity:
-
Datasheet Tech Support
PRODUCT DETAILS
SPECIFICATIONS |
|
---|---|
PRODUCT NAME |
ANKS1B Polyclonal Antibody, Cy5 Conjugated |
CONJUGATION |
Cy5 |
HOST |
Rabbit |
SOURCE |
KLH conjugated synthetic peptide derived from human ANKS1B/AIDA1 |
IMMUNOGEN RANGE |
|
CLONALITY |
Polyclonal |
ISOTYPE |
IgG |
CONCENTRATION |
1ug/ul |
PURIFICATION |
Purified by Protein A. |
STORAGE BUFFER |
Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. |
STORAGE CONDITION |
Store at 4°C for 12 months. |
TARGET |
|
---|---|
GENE ID |
|
SUBCELLULAR LOCATION |
|
SYNONYMS |
AIDA 1; AIDA-1; Amyloid-beta protein intracellular domain-associated protein 1; Anks1b; Ankyrin repeat and sterile alpha mot domain-containing protein 1B; ANS1B_HUMAN; E2A-PBX1-associated protein; EB-1. |
BACKGROUND |
The _-Amyloid protein precursor (AbPP) is a widely expressed transmembrane protein that is processed into the b-Amyloid (Ab) peptide, which accumulates in insoluble plaques in the brain of Alzheimer_s disease patients and AbPP intracellular domain (AID). AID may function as a pro-apoptotic peptide, a regulator of calcium homeostasis and a molecule involved in transcriptional regulation. The AID associated protein 1 (AIDA-1) is highly expressed in the brain and is regulated by AbPP. It interacts with AbPP to play a role in brain development. AIDA-1 also interacts with coilin in Cajal bodies to regulate pre-mRNA splicing. |
APPLICATION DILUTION |
IF(IHC-P)(1:50-200) |