Adenylosuccinate Lyase Antibody, Cy5.5 Conjugated
- Size: 100ul
- Application: IF(IHC-P), IF(IHC-F), IF(ICC)
- Reactivity: Human, Mouse
- Predicted Reactivity: Rat, Dog, Cow, Pig, Horse
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Datasheet
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PRODUCT DETAILS
SPECIFICATIONS |
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PRODUCT NAME |
Adenylosuccinate Lyase Antibody, Cy5.5 Conjugated |
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CONJUGATION |
Cy5.5 |
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HOST |
Rabbit |
| SOURCE |
KLH conjugated synthetic peptide derived from human Adenylosuccinate Lyase |
| IMMUNOGEN RANGE |
185-280/484 |
| CLONALITY |
Polyclonal |
| ISOTYPE |
IgG |
| CONCENTRATION |
1ug/ul |
| PURIFICATION |
Purified by Protein A. |
| STORAGE BUFFER |
Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. |
| STORAGE CONDITION |
Store at 4°C for 12 months. |
TARGET |
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| GENE ID |
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| SUBCELLULAR LOCATION |
Cytoplasm |
| SYNONYMS |
Adenylosuccinase; Adenylosuccinate lyase; ADSL; AMPS; ASase; ASL; PUR8_HUMAN. |
| BACKGROUND |
Adenylsuccinate lyase is involved in both de novo synthesis of purines and formation of adenosine monophosphate from inosine monophosphate. It catalyzes two reactions in AMP biosynthesis: the removal of a fumarate from succinylaminoimidazole carboxamide (SAICA) ribotide to give aminoimidazole carboxamide ribotide (AICA) and removal of fumarate from adenylosuccinate to give AMP. Adenylosuccinase deficiency results in succinylpurinemic autism, psychomotor retardation, and , in some cases, growth retardation associated with muscle wasting and epilepsy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]. |
| APPLICATION DILUTION |
IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200) |