Recombinant Coronavirus Spike Protein (SARS-CoV-2; His tag)

Glycoprotein that enables viral entry into the host cell

Product # : P1528
P1528-10:10 μg
P1528-50:50 μg
Product Support
Phone: (+91)-11-45035753
Order Information
Phone: (+91)-11-45035753


SARS-CoV is an enveloped, single and positive-stranded RNA virus. Cell entry of severe acute respiratory syndrome coronavirus (SARS-CoV) is mediated by the viral spike (S) protein. The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. For viral entry, the surface unit (S1) of SARS S binds to the cellular receptor angiotensin-converting enzyme 2 (ACE2) and the transmembrane unit (S2) then fuses the viral membrane with a host cell membrane. The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity, during infection with SARS-CoV. Because the S protein of SARS-CoV is involved in receptor recognition, as well as virus attachment and entry, it represents one of the most important targets for the development of SARS vaccines and therapeutics.

Product Information

AppearanceLiquid protein
HandlingCentrifuge the vial prior to opening.
Molecular Weight140 kDa (His-tag)
Shelf Life12 months
Storage Temperature-20°C
UsageFor Research Use Only! Not to be used in humans
Gene SourceCoronavirus
SourceE. coli
Shipping ConditionGel Pack
Physical Form DescriptionLiquid
Amino Acid SequencePeptide composed of full length spike protein sequence of 1282 amino acids.
Purity By>90%