Human CellExp™ PDGF-CC, Human Recombinant

Potent mitogen for a variety of cell types

Product # : P1526
SKU-Size:Size
P1526-10:10 μg
P1526-50:50 μg
Product Support
Email: customerservice@biolinkk.com
Phone: (+91)-11-45035753
(+91)-11-28753658
Order Information
Email: customerservice@biolinkk.com
Phone: (+91)-11-45035753
(+91)-11-28753658

Description


PDGF-CC is a member of the platelet-derived growth factor (PDGF) family, which was originally identified as a serum growth factor for fibroblasts, smooth muscle cells and glia cells. The PDGF family consists of proteins derived from four genes (PDGF-A, -B, -C, and -D) that form four disulfide-linked homodimers (PDGF-AA, -BB, -CC, and -DD) and one heterodimer (PDGF-AB). These proteins regulate diverse cellular functions by binding to and inducing the homo- or hetero-dimerization of two receptor tyrosine kinases (PDGF R alpha and R beta). PDGF-CC is expressed in multiple embryonic and adult cell types and tissues. PDGF-CC is involved in pathogenesis of neurologic diseases, cancer and fibrosis. The PDGF-CC ligand has also been shown to be involved in tumor growth by paracrine signaling through PDGFRα in malignant melanoma and cervical carcinoma.

Product Information


Accession #Q9NRA1
Alternate NamesPlatelet-derived growth factor C, PDGFCC; PDGF-CC, Fallotein, Spinal cord-derived growth factor, SCDGF, VEGF-E
AppearanceLyophilized powder
HandlingCentrifuge the vial prior to opening.
Molecular Weight16 kDa (6xHis tag at the C-terminus)
Protein Gi #56034
Shelf Life12 months
Storage Temperature-20°C
UsageFor Research Use Only! Not to be used in humans
Gene SymbolPDGFC
Gene SourceHuman
SourceHEK 293 cells
Shipping ConditionGel Pack
Physical Form DescriptionLyophilized
Reconstitution InstructionsCentrifuge the vial prior to opening. Reconstitute in sterile PBS (pH 7.4). Do not vortex.
Amino Acid Sequenceaa Val 235 - Gly 345
Purity By>95%